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INVEGA TRINZA TM (three-month paliperidone palmitate), the first and only schizophrenia medication to be administered just four times a year, providing the longest dosing interval available.
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For patients already stable on another oral antipsychotic (and known to tolerate aripiprazole), after the first ABILIFY MAINTENA injection, continue treatment with the antipsychotic for 14 consecutive days to maintain therapeutic antipsychotic concentrations during initiation of therapy.
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The investigators also determined that among 128 independent associations related to the 108 loci, enriched associations existed not only among genes expressed in the brain, but also among those expressed in tissues related to immunity, giving support to the theory linking the immune system to schizophrenia.
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Please share your positive and negative experiences with the drug, and compare it with other treatments you have used.
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ALKS 9070, a proprietary Alkermes molecule, is designed to provide patients with once-monthly dosing of a medication that, once in the body, converts into aripiprazole, a molecule that is commercially available under the name ABILIFY for the treatment of a number of central nervous system disorders.
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Weight gain: Significant weight gain has been observed with antipsychotic therapy; incidence varies with product.
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Hyperglycemia and Diabetes: Hyperglycemia, some cases extreme and associated with ketoacidosis, hyperosmolar coma or death has been reported in patients treated with atypical antipsychotics (APS), including RISPERDAL(R) CONSTA(R).
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As is similar to anxiety or depression, the connection between these symptoms and schizophrenia is not understood.
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Dose reduction is recommended in the presence of moderate CYP3A4 inhibitors.
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Invega, should be held responsible for these side effects.
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